Vitamin Information Center

Last week, we reported that high consumption of sugar-sweetened drinks seems to increase the risk for type 2 diabetes among African-American women. In the most recent issue of the Archives of Internal Medicine, investigators from England reported that high levels of vitamin C in the blood are associated with a substantially decreased risk of diabetes.

The researchers studied a population of people, ranging from age 40 to age 75, who completed food questionnaires. The study population was followed for 12 years - in that time, 735 cases of diabetes were identified among 21,831 health individuals. After analyzing the information from the food questionnaires, the researchers found that individuals with high vitamin C levels in the blood were substantially less likely to develop diabetes. They found that higher fruit and vegetable intake was also associated with a significantly decreased risk of diabetes.

These findings highlight a potentially important public health message - promoting a diet rich in fruits and vegetables could help in the prevention of diabetes.

An abundance of vitamin C in the diet may help lower a person’s risk of developing type 2 diabetes, new research suggests.

In a study of middle-aged and older men and women, those with the highest blood levels of vitamin C were significantly less likely to develop diabetes over 12 years than those with the lowest levels, researchers found.

Fruits and vegetables are the main source of vitamin C in Western diets, and blood levels of vitamin C are good markers of fruit and vegetable intake, Dr. Nita G. Forouhi, at the Institute of Metabolic Science at Addenbrooke’s Hospital, Cambridge, England, and colleagues note.

The current findings “re-endorse the public health message of the beneficial effect of increasing total fruit and vegetable intake,” the investigators wrote in Archives of Internal Medicine.

Forouhi’s team followed 21,831 healthy men and women who were 40 to 75 years old for the development of type 2 diabetes. At study entry, all participants provided detailed health and lifestyle information, as well as blood samples, which investigators used to determine vitamin C levels.

Over the course of the study, 423 men and 312 women developed type 2 diabetes, an overall rate of 3.2 percent.

According to the investigators, the likelihood of developing diabetes was 62 percent lower in men and women with the highest circulating vitamin C levels, relative to men and women with the lowest vitamin C levels.

Factoring out other characteristics associated with diabetes risk, such as older age, gender, family history, alcohol intake, physical activity, smoking status and body weight did not significantly alter these associations.

These data offer “persuasive evidence of a beneficial effect of vitamin C and fruit and vegetable intake on diabetes risk,” Forouhi and colleagues conclude.