Vitamin Information Center

Large sectors of the U.S. population are deficient in vitamin B6, according to a new study conducted by researchers from Tufts University and published in the American Journal of Clinical Nutrition.

The researchers warned that signs of deficiency emerged even among those meeting or exceeding the recommended dietary intake, and among those taking supplements.

“Across the study population, we noticed participants with inadequate vitamin B6 status even though they reported consuming more than the Recommended Daily Allowance of vitamin B6, which is less than two milligrams per day,” researcher Martha Savaria Morris said.

The Recommended Daily Allowance (RDA) for vitamin B6 is 1.3 milligrams per day for people between the ages of 19 and 50, 1.5 milligrams per day for women over the age of 50 and 1.7 milligrams per day for men over 50.

Researchers analyzed blood samples from 7,822 people of all ages, down to one year old, who participated in the 20043-04 National Health and Nutrition Examination Survey. They measured blood levels of pyridoxal 5′- phosphate (PLP), the biologically active form of the vitamin.

Eleven percent of those taking vitamin B6 supplements had PLP levels indicating deficiency, while 25 percent of those not taking supplements were vitamin deficient.

Male smokers, non-Hispanic African-American men and people of both sexes over the age of 65 were more likely to be vitamin B6 deficient. Women of childbearing age were also at increased risk for deficiency, especially those who had a history of oral contraceptive use.

Among women who did not take vitamin B6 supplements but did take oral contraceptives, 75 percent came up deficient in the vitamin.

The scientists called for more research into this connection, noting that it is possible that vitamin B6 is stored in a different way in women who take oral contraceptives, thus making blood concentration a less useful marker.

Foods rich in vitamin B6 include nuts, vegetables, whole grains and meats.

Sources for this story include: www.foodnavigator-usa.com.

Advertisements promise younger, more beautiful skin. Here’s what we know and don’t know about wrinkle reducers.

Wrinkles! They’re every mature woman’s nightmare.

Many women are scouring drugstore shelves and taking notes on TV beauty ads, searching for a facelift in a bottle. TV commercials are flashing models pushing formulas that promise to make your skin look youthful and tight as the skin on a drum-but much lovelier.

The American Society for Nutrition recently conducted a study aimed at discovering the connections between “nutrient intakes and skin-aging appearance.”

The society used data from the first National Health and Nutrition Examination Survey. Researchers looked into connections between “nutrient intakes” and skin aging in 4,025 women ages 40 to 74. Dermatologists conducted clinical examinations of the women’s skin.

Skin-aging appearance was defined in the study as “having a wrinkled appearance, senile dryness, and skin atrophy (thinning).”

Skin aging was found significantly in older women. As if we didn’t know it. “Women with a wrinkled appearance, dryness, and thinning skin were more likely to be white, have lower family Income, be postmenopausal, have higher exposure to the sun, and less likely to be physically active,” the researchers stated.

Cigarette smoking is a well-established Independent risk factor for facial wrinkling and skin aging, the researchers noted.

Vitamin A has long been said to have anti-wrinkle properties. It is used commonly in the cosmetics industry as a topical anti- wrinkle agent. Clinical trials, however, have failed to show this beneficial effect-at least when taken orally, the study said.

The researchers, however, found that women with a wrinkled appearance had lower vitamin A intakes-supporting the evidence that vitamin A just may benefit skin-aging appearance.

“We also found that women with a wrinkled appearance also had lower protein Intakes,” they wrote. Lower protein Intakes in older adults were shown to Increase skin fragility.

The researchers determined that vitamin C and llnoleic acid were warriors In the battle against wrinkles. Llnoleic acid is found in soybean oils, green leafy vegetables, and nuts. Vitamin C is in citrus fruits, some other fruit juices, and tomatoes.

Current dietary recommendations promote higher consumption of fruit, vegetables, and fish.

So, fighting wrinkles may be yet another motivation to eat healthy. This was said to be the first study to examine the effects of nutrients, rather than supplements on skinaging appearance.

Now, do over-the-counter wrinkle creams really reduce the appearance of fine lines and wrinkles? This depends on a number of factors.

A multitude of wrinkle creams and lotions sold in drugstores and department stores promise to reduce wrinkles and prevent or reverse damage caused by the sun.

But do they work? Some research suggests that wrinkle creams have ingredients that may diminish wrinkles. But many of these ingredients haven’t undergone scientific research to prove their benefit, according to Mayo Clinic physicians.

Creams and lotions may slightly improve the looks of your skin, depending on how long you use the product and the type and amount of the active ingredient.

Some common ingredients are found in these anti-wrinkle creams:

Retinol-This is a vitamin A compound and the first antioxidant to be put in nonprescription wrinkle creams. Antioxidants are substances that neutralize free radicals, experts explain. Free radicals are unstable oxygen molecules that break down skin cells and cause wrinkles.

A prescription topical treatment called tretinoin is approved by the FDA for treating wrinkles. “That and Differin have been proven to be effective and are ones I prefer,” said Dr. J. Ben Hengy, a Michigan plastic surgeon.

The FDA also has approved a wrinkle “filler” called Radiesse. It is injected and temporarily corrects “smile” lines. Radiesse is costly; the cheapest rate we found was about $850 a year for injections. Many patients also use muscle-relaxer Botox around the eyes and forehead.

Hydroxy acids-These are synthetic versions of acids from sugar- containing fruits. These acids are exfoliates. They remove the upper layer of old dry skin and stimulate the growth of new skin.

Coenzyme Qw-It’s a nutrient that helps regulate energy production in cells.

Copper peptides-They stimulate the production of collagen and may enhance the action of antioxidants.

Kinetin-It helps the skin retain moisture and stimulates the production of collagen.

Tea extracts-Green and black tea are said to contain compounds with antioxidant and anti-inflammatory properties. Green tea extracts are commonly found In wrinkle creams.

Sad to say, but you’ll have to dab on wrinkle creams once or twice a day for many weeks before noticing any improvement. And once you stop, your skin will likely return to its original wrinkled appearance, according to dermatologists.

So, it may well be that what you eat, more than what you dab on your skin, has the most beneficial effect in the war against wrinkles. Also, it’s reassuring to know that real beauty Is on the inside, not the outside.