Vitamin Information Center

The August 20, 2008 edition of the Journal of the American Medical Association (JAMA) reported that B Vitamins did not work effectively to prevent death or cardiovascular events in a population of patients with coronary artery disease or aortic valve stenosis. In the wake of this report, we’ve seen a vocal response from industry, claiming that the study is not credible, as it failed to acknowledge elements that could have altered the conclusions presented.

The study, conducted from 1999 through 2006, on 3,096 patients in two Norwegian hospitals, was headed by Dr. Marta Ebbing, M.D. at Haukeland University Hospital. Patients’ concerns about taking B vitamins to ward off cardiovascular problems, but at the same time, increasing the chance of cancer, resulted in the study being stopped prematurely.

The study divided participants into one of four groups; daily oral treatment of folic acid plus vitamin B12 and vitamin B6; folic acid plus vitamin B12; vitamin B6 alone; or a placebo. The doses of vitamins used in the groups were 0.8 milligrams of folic acid, 0.4 milligrams of B12 and 40 milligrams of B6.

One of many questions that quickly arose in study feedback was whether beta blockers, statins and anti-platelets were used for the duration of the study. The participants started the study while in their mid-60’s, and more than 75 percent of them had already been using the above mentioned drugs for existing heart disease.

Another issue with the study was that Norway does not add folic acid to its wheat as is done in the US, ostensibly, because they do not believe that fortified foods are necessary. This, in turn, meant that any folic acid, B-6 or B-12 through supplementation or other food that participants may have been taking at home was not factored into the study, and could have affected the results. Analysts also believe that the study involved too narrow a section of the population, and could not provide a proper answer to what B vitamin does for healthy people, arguing that folic acid supplementation should be considered from a preventative standpoint only.

With so many variables unaccounted for in the study, one might wonder how it still went on for years without intellectual intervention. Hindsight though, is 20/20, and the missing factors are quite evident in retrospective analysis.

Dr. Andrew Shao, of the Council for Responsible Nutrition (CRN), in an interview with NPIcenter, explained that groups like the CRN “try to caution against over-interpretation of results and broad sweeping conclusions that you hear from some people.” Shao added “B vitamins may not work for people who already have heart disease, but these studies don’t answer the question of whether the healthy population, if they take B vitamins on a regular basis over the course of decades, may be at a lower risk for heart disease.”

Industry frequently complains, in cases like this, about study design.

Shao observed, “The study was actually pretty well designed. Every study has limitations. No matter what, you’re always going to have limitations to a study, and it’s important to identify those limitations; if you’re overly critical of them, that is a really difficult position to have because no one is ever going to conduct the absolute perfect study that answers every question that anyone would possibly want to ask in the world.”

Despite what seem like flaws in the study, it is important to remember that a be-all, end-all cure was not the final goal for Dr. Ebbing and colleagues. The study was to see if B vitamin use would lower homocystein levels and help those with existing heart disease, not simply if B vitamin use would prevent heart disease, and it seems to have done that.

“You have a tool box of prevention, and there are all kinds of tools in there that you can use to try and keep yourself healthy and avoid disease,” said Shao. “Using supplements is just one of these tools, among a whole bunch. It is not THE tool, it is A tool. You have other components such as diet, stress, exercise [and] genetics, which is a tool you can’t do anything with but you’ve still got it. Supplements are just one of those tools. If that’s your outlook and you understand it… that’s where the benefit will be seen.”

With the growing awareness of the importance of healthy food, many people are also becoming vegetarian because it matches the kind of low fat, high fiber diet recommended by dieticians and doctors. Concern about the environment is another factor as people become more aware of the effect raising animals for their meat is having on the environment. Or you may be concerned about wasting world food resources by using land to raise animals for meat instead of growing crops that can feed more people directly.

Animals need far more water than grain crops. According to the USDA, growing the crops necessary to feed farmed animals requires nearly half of the United States’ water supply and 80% of its agricultural land. Additionally, animals raised for food in the U.S. consume 90% of the soya crop, 80% of the corn crop, and a total of 70% of its grain.

One acre of pasture produces an average of 165 pounds of beef; the same acre can produce 20,000 pounds of potatoes.

Vegetarian diets have been found to satisfy the nutritional needs for all stages of life, and large-scale studies have shown vegetarianism to increase longevity, improve health, and significantly lower the risks of many diseases.

Studies show that vegetarian diets help to keep body weight under control and reduce the risk of heart disease, osteoperosis and many cancers - particularly lung cancer and colon cancer. Vegetarians tend to have lower levels of cholesterol, lower blood pressure, and less incidence of dementias such as Alzheimer’s. Vegetarian diets that are low in saturated fats have been successfully used to reverse severe coronary artery disease.

It was once widely believed that vegetarians had to carefully combine plant protein sources in each meal in order to obtain all the essential vitamins, minerals and amino acids needed to stay healthy. However, scientific studies have shown that the human body can store essential amino acids and combine them as necessary. So, while combining beans and rice, or peanut butter and bread produces a complete protein, it’s not necessary to consciously do this at every meal. If you eat a varied diet and adequate calories, combining proteins is not an issue.

Vegetarian diets are lower in saturated fats, cholesterol, and animal protein. They’re also high in folate, anti-oxidant vitamins like C and E, carotenoids, and phytochemicals.

Some famous vegetarians are Leonardo Da Vinci, Charles Darwin, Socrates, Plato, Sir Isaac Newton and Thomas Edison. Famous modern day vegetarians include Bryan Adams, Alicia Silverstone, Liv Tyler, Jerry Seinfeld, Kim Basinger, and Paul McCartney.

If you are new to vegetarianism, The Higher Taste by Srila Prabhupada is a great beginners booklet. Not only does it explain vegetarianism clearly but it also gives some delicious easy to follow recipes.

There are many vegetarian websites today that provide many delicious recipes. There are a large variety of vegetarian recipes available from Italian and Greek cuisine to Middle Eastern, Indian and Chinese cuisine.

Why are so many Americans heading towards, if not already battling an obesity problem? What are the main factors to this growing epidemic and what can we do to stop it?

Let’s take an eye opening look into the downfall of our diet and our changing culture. Here we will outline the cause and effect and give you the solution to stop the rising obesity problem.
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