Vitamin Information Center

CHRONIC pain in women may be related to low levels of vitamin D, the nutrient made by the skin when exposed to sunlight.

Researchers who studied nearly 7000 British 45-year-olds found that almost 15 per cent of women with the lowest levels of the vitamin reported experiencing chronic pain - nearly twice the 8.2 per cent prevalence reported among women with higher readings.

However, vitamin D levels appeared to make no difference to the number of men who reported pain symptoms - leaving the study’s authors perplexed as to whether lack of vitamin D in women was the cause.

The authors noted that a disease caused by extreme vitamin D deficiency, osteomalacia, was known to cause bone pain.

The research concluded that further studies were required to establish whether pain would be lessened if patients increased their vitamin D intake.

For the study, published yesterday in the journal Annals of the Rheumatic Diseases, the authors included medical data from 6824 Britons who were examined between 2002 and 2004, when they were aged 45. Information was collected on their smoking and alcohol habits, time spent outdoors, time spent watching television or at a computer and dietary supplements, including vitamin D.

Samples of their blood werealso analysed for

levels of 25-hydroxy-vitaminD (25(OH)D), which is a metabolised form of the vitamin and a marker for vitamin D levels.

The lowest prevalence of chronic widespread pain (8.2per cent) was reported in women with 75 to 99 nanomoles of 25(OH)D per litre of blood.

The rate was 14.4 per cent for women with less than 25nmol/l, and 14.8per cent for women with 25-49nmol/l.

John Eisman, director of the bone and mineral research program at the Garvan Institute of Medical Research, said the study was interesting but by its design could not “unravel” whether lower vitamin D was causing the pain, or vice-versa.

Professor Eisman, who is also an endocrinologist at Sydney’s St Vincent’s Hospital, agreed that more studies were required.

In the meantime, if doctors were faced with patients battling chronic pain, “it might be worth giving them vitamin D, to see if it makes a difference”, he said.

Popping vitamin pills ‘like sweets’ could seriously damage your health, warn experts

HEALTHY people who take vitamin supplements were last night urged to be careful after research suggested they may do more harm than good.

Welsh health experts advised people to meet their nutritional needs by eating five portions of fruit and vegetables a day.

There were also calls for tighter regulation of the sale of vitamins and minerals, which the public can buy “like sweets”, according to dietary advice groups.

The warning comes after researchers found that people who take antioxidant supplements, including vitamins A and E, to try to keep diseases such as cancer at bay, could in fact be interfering with their natural body defences and may be increasing their risk of an early death by up to 16%.

About 12 million Britons supplement their diets with vitamins and the industry is worth about £330m a year.

Paul Walker, chairman of the National Public Health Association Cymru, said: “We all need vitamins up to a certain level, but there is a misconception that taking more must be good for you.

“The evidence shows that this isn’t true. Having too much does no good and, in fact, could do people harm.

“The key is to have a very varied diet with at least five portions of fruit and vegetables per day.

“More regulation of this industry is probably required.”

Antioxidants, including vitamins A, E, C and beta-carotene and selenium, are said to mop up disease-causing compounds called free radicals. It is this action that researchers say may cause problems with the defence system.

The research by Copenhagen University, released by the influential Cochrane Library, applied only to synthetic supplements and not to vitamins that occur naturally in vegetables and fruit.

Researchers carried out a review of 67 studies on 230,000 healthy people and found “no convincing evidence” that any of the antioxidants helped to prolong life expectancy but some “increased mortality”.

They found that vitamin A supplements increased the risk of death in healthy people by 16%. Taking beta-carotene was linked to a 7% increased risk, while regular users of vitamin E supplements increased the risk of an early death by 4%.

Although the review found no significant detrimental effect caused by vitamin C, it found no evidence that it helped ward off disease. Millions take it in the hope of avoiding a common cold.

Goran Bjelakovic, who led the review, said: “We could find no evidence to support taking antioxidant supplements to reduce the risk of dying earlier in healthy people or patients with various diseases.

“If anything, people in trial groups given the antioxidants beta-carotene, vitamin A and vitamin E showed increased rates of mortality.”

Catherine Collins of the British Dietetic Association said: “This study is deeply worrying and shows that there should be more regulation for vitamins and minerals.

“The public can buy vitamins as easily as sweets. They should be treated in the same way as paracetamol with maximum limits on the dosage.”

Camille Clarke, a naturopathic nutritionist, based at the Natural Health Clinic in Cathedral Road, Cardiff, backed calls for tighter controls.

“It [the industry] needs to be regulated, vitamins are too freely available,” said Camille, who urged people to opt for naturally- occurring vitamins.

“People read things in magazines and they are taking huge amounts of vitamins and minerals but have a terrible diet.

“There’s no point in taking vitamins if you don’t have a healthy diet. You should only take them if you have a health problem and only for a little while.”

Denise Parish, a lecturer in dietetics at the University of Wales Institute, Cardiff, and a state registered dietician of 14 years, said: “As a general rule there is no evidence to say taking vitamins is of any benefit. Actually eating the foods that contain them is the best way of getting antioxidants.”

She said the only people who should take vitamin supplements are those who have particular health problems or pregnant women who are advised to take folate.

The chief medical officer for Wales, Dr Tony Jewell, said: “A good balanced diet which includes fresh fruit and vegetables will always provide individuals with the vitamins that they need.

“We would always advise people not to rely on such supplements as their primary source of vitamin intake.”