Vitamin Information Center

Bubonic Plague
Synonyms
Infection with Yersinia pestis

Definition
Bubonic plague is caused by the bite of a rat flea which
is infected with the bacterium Yersinia pestis. The
onset of the disease is characterized by fever, headache,
joint pain, malaise and muzziness. A swelling of the
lymph nodes causes painful bubons at the neck, in
the armpits and the groins. Due to hemorrhages, these
bubons become black. After suppuration occurs within
the bubons they rupture. Spreading of the bacteria into
the skin causes subdermal bleedings and acral necroses.
Without treatment, in 25–50% of cases, a hematogenic
spread of germs leads to plague sepsis.

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