Atovaquon + Proguanil (Malarone®)
Definition
Atovaquon interferes with the transport of electrons
inside the plasmodia, proguanil impairs protein
metabolism. The combination of both substances is
effective against all forms of malaria. Treatment is carried
out for three days. As water solubility of atovaquon
is poor, it should be taken with a fatty meal
to improve intestinal resorption. Side effects of the
drugs are headache, cough and gastrointestinal symptoms
(primarily vomiting and diarrhea).
Tags: cough, drugs, electrons, forms of malaria, gastrointestinal, gastrointestinal symptoms, headache, malaria treatment, malarone, plasmodia, protein metabolism, vomiting and diarrhea, water solubility
